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One test provides a snapshot. Two tests, spaced 3–6 months apart, show a trajectory:
Is your treatment slowing resorption?
Are lifestyle or hormone changes moving the needle?
Or is breakdown happening faster than expected?
How It Works
Urine-based — simple, needle-free collection.
Collect your second morning void (empty bladder once upon waking, then collect the next sample).
Avoid strenuous exercise for 24 hours before collection.
Results are creatinine-adjusted, so hydration doesn’t throw things off.
Clinicians often look for a 30%+ drop over ~6 months as a signal that therapy is working.
What You’ll Learn
Whether your skeleton is breaking down faster than it rebuilds.
How your body responds to therapies, supplements, or lifestyle shifts.
A trend line you can overlay with DEXA bone density or body composition.
Options
Single Test — $95
A starting point or spot check.
Baseline + Follow-Up Bundle — $175
Test now, repeat in 3–6 months.
The trajectory tells you far more than a single number.
Save when purchased together.
NTx is one piece of the puzzle. It doesn’t predict fractures on its own, and it shouldn’t be over-interpreted. Its real value is when it’s combined with:
DEXA bone density
Body composition scans
Family history, lifestyle, and therapy data
Think of it less as a verdict and more as a trend line in the bigger picture of bone health.
Bottom Line
The NTx Urine Test is a practical way to track bone resorption over time. On its own, it’s a snapshot — combined with DEXA and clinical context, it becomes a powerful tool for monitoring bone health trends.